ENDOCARDITA CERTA

AGENTUL ETIOLOGIC

TERAPIE RECOMANDATA

DE PRIMA INTENTIE

ALTERNATIVE

Streptococ - Pen - sensibil

Penicilina G ± aminoglicozid

Cefalosporine gen. III

Streptococ - Pen - rezistent

Aminopeniciline + aminoglicozid

Fluorchinolone gen III

Glicopeptide ( Teicoplanina )

Enterococ - ampi - sensibil

Aminopeniciline + aminoglicozid

Enterococ - ampi - rezistent

AminoPen + inh β lactamaze

± aminoglicozid

Glicopeptide / Carbapeneme

± aminoglicozid

Enterococ - genta - rezistent

AminoPen + inh β lactamaze

Glicopeptide / Carbapeneme

Enterococ vanco - rezistent

Linezolid

Cefalosporine gen. IV / Tazocin

Stafilococ auriu - meti - sensibil

Oxacilina + aminoglicozid

Fluorchinolone

Cefalosporine gen I

Stafilococ auriu - meti - rezistent

Glicopeptide / Carbapeneme

± aminoglicozid

Linezolid

Cefalosporine gen. IV

HACEK

Ceftriaxona

± aminoglicozid

AminoPen + inh β lactamaze

± aminoglicozid

BGN

Cefalosporine gen. III / Tazocin + aminoglicozid

Fluorchinolone + aminoglicozid

Carbapeneme

Bacil piocianic

Carbapeneme

Cefalosporine gen. IV

Cefalosporine gen. III / Tazocin

Fluorchinolone

fungi

Voriconazol

Caspofungin

Amfotericina B

Fluconazol